Biomateriales II

The Biomaterials II group of the Institute of Polymer Science and Technologies has 20 years of experience working in the area of ​​biomaterials and tissue engineering. The group is specialized in the synthesis and optimization of new organic and inorganic based materials, and in the development of new technologies for processing these materials for medical applications.

The group has extensive experience in the design, synthesis and development of molecules or organic materials with unconventional properties in an efficient and environmentally friendly way, as well as in ceramic, polymeric and hybrid materials processing. This experience has allowed the design of new synthesis routes that have solved, for example, four challenges of the american consulting company InnoCentive, challenges considered impossible or very difficult to solve by the institutions that hired their services.

In the field of organic-based materials with unconventional properties, among others, it has been possible to design, synthesize and develop a new class of flexible materials, with a high refractive index with anti-inflammatory and bactericidal properties suitable for use as intraocular lenses.

In ceramic materials field, the specific conditions for the synthesis of hydroxyapatite nano and microparticles have been studied with chemical substitutions that allow them to be osteoinductive, in addition to the osteoconductive properties that are generally attributed in the literature, it has been possible to modulate their resorbability and its mechanical properties. In the polymer field, methods for preparing scaffolds of different acrylic compounds have been developed. In addition, sol-gel technology has been used to develop hybrid materials of titanium oxide with polyurethanes and silicon oxide with different polysaccharides including hyaluronates and alginates.

Colloidal processing methods have been developed for dense and porous ceramics and methods for processing porous polymeric materials by spinoidal separation, freeze drying, cryopolymerization and electrospinning. In the last 5 years the activity of the group in the area of materials processing has been directed to the preparation of porous scaffolds in 3 dimensions by means of 3D printing technologies of polymer melts and of constructs by means of 3D bioprinting of biological material contained or encapsulated in natural polymers. This last project has been carried out within the framework of the European space agency, giving rise to a doctoral thesis for bioprinting of tissues in long-term space travel. This work has been incorporated into the CSIC white paper to face the challenges of the future. The group belongs to the CIC platform for the development of additive manufacturing FAB3D: https://pti-fab3d.csic.es/

Biomaterials II Web