The Biomaterials Group II has 25 years of experience working in the area of ​​biomaterials and tissue engineering. The group is specialized in the synthesis and optimization of new organic and inorganic-based materials, and in the development of processing technologies for medical applications.

The group has extensive experience in the design, synthesis and development of environmentally friendly non-conventional organic materials, as well as in the processing of ceramic, polymeric and hybrid materials. This experience has allowed the design of new synthesis routes that have solved four challenges of the American consultancy InnoCentive.

In the last 5 years, the group's activity in the area of ​​materials processing has been directed towards the preparation of porous scaffolds using 3D printing and bioprinting technologies, including a cellular component in the composition. This last project has been carried out within the framework of the European Space Agency, giving rise to a doctoral thesis for tissue bioprinting in long-term space travel. This work has been incorporated into the CSIC white paper to face the challenges of the future. The group belongs to the CSIC platform for the development of FAB3D additive manufacturing: https://pti-fab3d.csic.es/
 

Main publications

Cristina Banda Sánchez, Nieves Cubo Mateo, Laura Saldaña, Alba Valdivieso, Julie Earl, Itziar González Gómez, Luis M. Rodríguez-Lorenzo; Selection and Optimization of a Bioink Based on PANC-1-Plasma/Alginate/Methylcellulose for Pancreatic Tumour Modelling; Polymers 2023 15, 3196. 

DOI: https://doi.org/10.3390/polym15153196
URI: http://hdl.handle.net/10261/332060
 

Aurora C. Hernández-González, Lucia Téllez-Jurado; Luis M Rodríguez-Lorenzo; PREPARATION OF COVALENTLY BONDED SILICA-ALGINATE HYBRID HYDROGELS BY SCHIFF BASE AND SOL-GEL REACTIONS; Carbohydrate polymers 267 (2021). 118186

DOI: https://doi.org/10.1016/j.carbpol.2021.118186
URI: http://hdl.handle.net/10261/240351
 

Raúl Rosales-Ibáñez, Nieves Cubo-Mateo, Amairany Rodríguez-Navarrete, Arely M González-González, Tomás E Villamar-Duque, Leticia O Flores-Sánchez, Luis M Rodríguez-Lorenzo; Assessment of a PCL-3D printing-Dental Pulp Stem Cells triplet for bone engineering Polymers 2021, 13(7), 1154;

DOI: https://doi.org/10.3390/polym13071154 
URI: http://hdl.handle.net/10261/236626 
 

Nieves Cubo-Mateo, L.M. Rodríguez-Lorenzo; Design of Thermoplastic 3D-Printed Scaffolds for Bone Tissue Engineering: Influence of Parameters of “Hidden” Importance in the Physical Properties of Scaffolds; Polymers 2020, 12, 1546; 

DOI: https://doi.org/10.3390/polym12071546
URI: http://hdl.handle.net/10261/216708
 

Aurora C. Hernández-González, Lucia Téllez-Jurado; Luis M Rodríguez-Lorenzo; Alginate hydrogels for bone tissue engineering, from injectables to bioprinting: A Review; Carbohydrate polymers 229, Año 2020, # 115514 

DOI: https://doi.org/10.1016/j.carbpol.2019.115514
URI: http://hdl.handle.net/10261/193039
 

Main projects

Ortesis mioeléctricas con electrodos implantables: optimizando la reconstrucción biónica tras lesiones graves de nervio periférico. PI22/00862 financiado por Instituto de Salud Carlos III y por FEDER Una manera de hacer Europa. 

  • DESDE: 01/01/2023                                                        
  • HASTA: 31/12/ 2026
  • INVESTIGADOR/A PRINCIPAL: ANDRES ALFONSO MALDONADO MORILLO
  • FUNDACION INVESTIGACION BIOMEDICA HOSPITAL DE GETAFE. responsable CSIC: Luis M Rodríguez Lorenzo
  • Presupuesto: € 129.470,00  

New noninvasive technology for inhibition of solid tumor growth based on low intensity ultrasounds. Proyecto PID2021-128985OB-I00 financiado por MICIN/AEI /10.13039/501100011033/ y por FEDER Una manera de hacer Europa.

  • DESDE: 1 de Septiembre de 2022
  • HASTA: 31 Agosto de 2025
  • INVESTIGADOR/A PRINCIPAL: Luis María Rodríguez Lorenzo, Itciar González Gómez.
  • Presupuesto: € 150000

DISEÑO Y SINTESIS DE NANOPARTICULAS MOLECULARES Y BIOMOLECULARES CON ACTIVIDAD ANTIBACTERIANA NANOMECANICA Y FOTODINAMICA. Proyecto PID2020-114347RB-C31 financiado por MINISTERIO DE CIENCIA E INNOVACION.

  • INVESTIGADOR/A PRINCIPAL: CHIARA ROMERO, JOSE LUIS
  • DESDE: 1 de Enero de 2021
  • HASTA: 31 Diciembre de 2023
  • Presupuesto: 133.100,00 €

DISEÑO Y SINTESIS DE NANODISPOSITIVOS BIOMOLECULARES SOSTENIBLES CON ACTIVIDAD ANTIMICROBIANA MECANICA. Proyecto TED2021-132122B-C22. Financiado por MINISTERIO DE CIENCIA E INNOVACION.

  • INVESTIGADOR/A PRINCIPAL: CHIARA ROMERO, JOSE LUIS
  • DESDE: 1 de Diciembre de 2022
  • HASTA: 30 Noviembre de 2024
  • Presupuesto 150.650,00 €